Studies on the Organophosphorus Insecticides

During an investigation of organophosphorus insectiside, the present author found that the reactions of O,O-dialkyl phosphorochloridate or O,O-dialkyl phosphorochloridothioates with sodium salts of β-keto-esters or nitriles give new phosphoroates or phosphorothioates containg phenylacrylate or phenylacrylonitrile radicals, but do not give phosphonates.

The reactions of trialkylphosphites with α-halo- or α,α-dihalo-phenyl-β-keto-esters or nitrils also gave phosphoroates. Some phosphoroates prepared by this methods have high insecticidal activity.