Relation between the Extracellular Accumulation of L-Glutamic Acid and the Excretion of Phospholipids by Penicillin-treated Corynebacterium alkanolyticum

The addition of penicillin (50 u/ml) to the cells of Corynebacterium alkanolyticum No. 314 growing on n-paraffins medium at the logarithmic growth phase was the most suitable for the extracellular accumulation of L-glutamic acid and the excretion of phospholipids.

The relation between the extracellular accumulation L-glutamic acid and the excretion of phospholipids in the presence of penicillin was very close and specific. The kinds of phospholipids excreted and their fatty acid components were the same as those of intracellular phospholipids.