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Formation of Acetylene Dicarboxylic Acid and Its Esters with 2-Butyne-1,4-diol from 2-Butyne-1,4-diol by Fusarium merismoides B11
Authors:Teruzo Miyoshi  Hideo Sato  Tokuya Harada
Institution:The Institute of Scientific and Industrial Research, Osaka University, Yamada-kami, Suita-shi, Osaka
Abstract:Several kinds of compounds were formed by Fusarium merismoides Bll when the fungus was grown in the medium containing 2-butyne-1,4-diol as the sole source of carbon. Four of these compounds were isolated by thin-layer chromatography and identified as acetylene dicarboxylic acid, an ester of acetylene dicarboxylic acid with 2-butyne-1,4-diol, an acetylated derivative of the ester, and cis-aconitic acid.
Keywords:cilostazol  oxidative stress  diabetic nephropathy  TGF-β  NF-κB
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