Nature of DNA and RNA Degradation in Escherichia coli Induced by Colicin E2 |
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Authors: | Akira Yanai Teruhiko Beppu Kei Arima |
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Institution: | Department of Agricultural Chemistry, Faculty of Agriculture, University of Tokyo, Tokyo |
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Abstract: | Lipogenesis in the fatty liver of rat, which was induced by feeding an amino acid unbalanced diet containing 8% casein supplemented with 0.3% dl-methionine, has been studied by measuring the incorporation of glycerol-1-14C, palmitate-1-14C, citrate-1,5-14C, pyruvate-1-14C and pyruvate-2-14C into various lipid fractions and 14CO2 during in vitro incubation of liver slices.The total radioactivity of liver lipid per 100 g of the body and the incorporation of each substrate into triglyceride in the lipid were significantly higher in the imbalance group than the control group. Conversion of each substrate to 14CO2 was not imparied in the imbalance group.It is evident from these results that the induction of this type of fatty liver is due mainly to the triglyceride synthesis by both the fatty acid synthesis and the transesterification of fatty acid.These results are considered to support the previous assumption in which acetate-1-14C was used as a precursor. |
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Keywords: | CAP 14-3-3 Lentinus edodes two-hybrid signal transduction |
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