Studies on Degradation of d-Biotin by Microorganisms |
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Authors: | Han-Chul Yang Masahiro Kusumoto Tatsurokuro Tochikura Koichi Ogata |
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Affiliation: | Department of Agricultural Chemistry, Kyoto University, Kyoto |
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Abstract: | During the course of investigations on the metabolism of d-biotin by microorganisms, the authors have found that a strain belonging to Endomycopsis effectively converted d-biotin into unknown biotin vitamers. The unknown biotin vitamers formed were isolated in crystalline form from the culture filtrate of a strain of Endomycopsis species and characterized as bisnorbiotin and bisnorbiotin sulfoxide by their physico-chemical and biological properties. The isolated vitamers were shown to support the growth of Bacillus subtilis, but not of Saccharomyces cerevisiae and of Lactobacillus arabinosus. The degradative pathway of d-biotin in microorganisms was also discussed. |
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Keywords: | Tripterygium hypoglaucum terpenoid NO production |
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