Synthesis of Some New Halogenated N-Thiazolyl Substituted Hydroxy Acid Amides and Their Use as Possible Fungicides

A large number of new N-thiazolyl, chloro-thiazolyl, brome-thiazolyl and iodothiazolyl amides of salicylic, hydroxy naphthoic acids, both halogenated and non-halogenated ones have been synthesised by condensing simple as well as halogenated thiazoles with different aromatic hydroxy acids, viz. salicylic, chloro- and bromo-salicylic, hydroxy naphthoic and bromo hydroxyl naphthoic acids. All these compounds are assayed for their fungicidal activity using Piricularia oryzae (Cav.), Helminthosporium oryzae and Carvularia lunata as the test fungi. An attempt has been made to establish a relationship between chemical structure and fungicidal activity.