Esterolytic Activity of Acid Carboxypeptidase from Aspergillus saitoi

Asymmetric reduction of aromatic ketones using chirally modified reagents prepared from sodium borohydride and optically active acids in the presence or absence of 1,2: 5,6-di-O-isopropylidene-α-d-glucofuranose produced the corresponding optically active alcohols with optical yields of 4 ~ 47%. The reagent prepared from sodium borohydride and 1 equivalent of l-malic acid in the presence of 2 equivalents of 1,2: 5,6-di-O-isopropylidene-α-d-gluco-furanose gave the highest yields.