Utilization of n-Paraffins and Vitamin B6 Production by Pichia guilliermondii Wickerham |
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Authors: | Naomichi Nishio Kenji Sakai Koji Fujii Tadashi Kamikubo |
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Institution: | Department of Fermentation Technology, Faculty of Engineering, Hiroshima University, Hiroshima |
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Abstract: | The accumulation of vitamin B6 by Pichia guilliermondii Wickerham NK–2 strain grown on hydrocarbon was investigated. Ammonium acetate was more effective than other nitrogen sources tested. Satisfactory utilization by the yeast strain was observed in n-alkanes of C10–C18, and n-pentadecane was the best for vitamin B6 production. Vitamin B6 was excreted in the cultural broth mainly in the form of pyridoxal, The maximal vitamin B6 production was approximately 25 mg per liter of the culture broth. |
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Keywords: | glycerol synthesis osmoregulation MAP-signaling pathway: upstream activation sequence Schizosaccharomyces pombe |
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