Ginsenoside Re improves skin barrier function in HaCaT keratinocytes under normal growth conditions |
| |
Authors: | Yuri Oh Hye-Won Lim |
| |
Affiliation: | 1. Department of Biological Sciences, Kangwon National University, Chuncheon, Korea;2. Shebah Biotech Inc., Chuncheon, Korea |
| |
Abstract: | Ginsenoside Re (Re), a major ginsenoside of ginseng, enhanced the cornified cell envelope (CE) formation in HaCaT keratinocytes under normal conditions. In HaCaT keratinocytes, Re was also able to upregulate filaggrin protein and caspase-14 activity in a concentration-dependent manner. These findings reasonably imply that Re possesses a desirable property of improving skin barrier function. |
| |
Keywords: | ginsenoside Re cornified cell envelope filaggrin caspase-14 HaCaT |
|
|