Ginsenoside Re improves skin barrier function in HaCaT keratinocytes under normal growth conditions |
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| Authors: | Yuri Oh Hye-Won Lim |
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| Institution: | 1. Department of Biological Sciences, Kangwon National University, Chuncheon, Korea;2. Shebah Biotech Inc., Chuncheon, Korea |
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| Abstract: | Ginsenoside Re (Re), a major ginsenoside of ginseng, enhanced the cornified cell envelope (CE) formation in HaCaT keratinocytes under normal conditions. In HaCaT keratinocytes, Re was also able to upregulate filaggrin protein and caspase-14 activity in a concentration-dependent manner. These findings reasonably imply that Re possesses a desirable property of improving skin barrier function. |
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| Keywords: | ginsenoside Re cornified cell envelope filaggrin caspase-14 HaCaT |
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