Isolation of Clostridium difficile from stored specimens and comparative susceptibility of various tissue culture cell lines to cytotoxin |
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| Authors: | Rodney A. Bowman Thomas V. Riley |
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| Affiliation: | Department of Anaerobic Microbiology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, U.S.A. |
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| Abstract: | Abstract Toxins A and B of Clostridium difficile were purified to homogeneity and some of their properties were examined. The toxins have similar LD100 values in mice, share some similarities in their amino acid composition, and are both sensitive to oxidizing agents. However, they have different isoelectric points and do not show any significant peptide homology. |
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| Keywords: | Cytotoxin enterotoxin, antibiotic-associated colitis |
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