Intercellular interactions as a reason for the influence of the erythrocyte concentration on the parameters of detergent hemolysis

Possible reasons are discussed for the abnormal erythrocyte concentration influence on the course of detergent hemolysis curves. The data obtained lead to a conclusion that erythrocyte plasma membrane properties and, as a consequence, the parameters of erythrocyte-detergent interaction are dependent on cell concentration. The dependence is more sharply expressed for concentrations 5.10(7) cell/ml. In the concentration range (5-20) X 10(7) cell/ml the state of erythrocyte membrane remains apparently unchanged.