Differences in survivability among F344 rats. |
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Authors: | S Tanaka N Tamaya K Matsuzawa O Miyaishi |
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Affiliation: | Laboratory Animal Research Facilities (LARF), National Institute for Longevity Sciences (NILS), Obu, Japan. |
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Abstract: | Important parameters to identify and develop appropriate animal models for longevity science include survivability, age-related disorders, and easy handling of aged individuals. It is found that F334/Du and F344/N have distinctive strain difference in these parameters. The finding suggests F334/Du and F344/N, even though they are historically siblings, need clearly separate identification when used as animal models for aging science, in particular, longevity science. |
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