Interferon-inducing action of polysaccharide-containing biopolymers from ginseng root and cell culture] |
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Authors: | T P Smolina T G Orlova O N Shcheglovitova N N Besednova |
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Institution: | Research Institute of Epidemiology and Microbiology, Siberian Department of the Russian Academy of Medical Sciences, Vladivostok. |
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Abstract: | Induction of interferon (IF) and tumor necrosis factor (TNF) under the action of two polysaccharide preparations of ginseng i.e. panaxan-1 (from ginseng root) and panaxan-2 (from ginseng cell culture) was studied. Both the preparations induced production of TNF and IF in human leukocytes. By its properties and the typing results the induced IF proved to be gamma-IF. The preparation from the ginseng cell culture in the doses used had a higher IF inducing activity which could be explained by the difference in the polysaccharide composition of the preparations. |
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