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Assignment of three rat integrin genes to Chromosome 19 (ITGB1), Chromosome 3 (ITGA4), and Chromosome 7 (ITGA5)
Authors:Claude Szpirer  Michèle Rivière  Josiane Szpirer  Göran Levan  Martine Jaspers  Sylie Vekemans  Jean-Jacques Cassiman
Affiliation:(1) Département de Biologie Moléculaire, Université Libre de Bruxelles, Rue des Chevaux, 67, B-1640 Rhode-St-Genèse, Belgium;(2) Department of Genetics, University of Gothenburg, Box 33031, S-40033 Göteborg, Sweden;(3) Center for Human Genetics, University of Leuven, Campus Gasthuisberg O & N, B-3000 Leuven, Belgium
Abstract:By means of somatic cell, hybrids segregating rat chromosomes, we determined the chromosome localization of three rat beta1 family integrin genes. ITGB1 was assigned to Chromosome (Chr) 19, ITGA4 to Chr 3, and ITGA5 to Chr 7. These chromosome assignments reveal or confirm homology between two pairs of rat and human chromosomes (rat Chr 3-human Chr 2; rat Chr 7-human Chr 12).
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