| 蛇伤药酒抗眼镜蛇毒的药效学研究 |
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| 引用本文： | 蒋三员,李景新,唐荣德,张健民,余南发,昌水平.蛇伤药酒抗眼镜蛇毒的药效学研究[J].蛇志,2003,15(3):17-19. |
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| 作者姓名： | 蒋三员 李景新 唐荣德 张健民 余南发 昌水平 |
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| 作者单位： | 广东省江门市新会中医院,广东江门,529100 |
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| 基金项目： | 江门市卫生局立项课题 (编号 :0 3 A0 3 3 ) |
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| 摘 要： | 目的探讨蛇伤药酒对眼镜蛇毒中毒的治疗效果。方法用中华眼镜蛇毒于家兔制作的病理模型并用蛇伤药酒于注毒局部外敷治疗，再进行中毒表现和血液指标等观察。结果与蛇毒组相比，药酒组局部和全身症状均较轻，死亡率较低；WBC、CK和CRP变化没有那么明显，PLT、PT和FBG水平基本没有变化。结论蛇伤药酒能减轻炎症反应，防止急性DIC发生和保护机体组织受损，故有较好的对抗眼镜蛇毒的作用。
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| 关 键 词： | 蛇伤药酒 眼镜蛇毒 药效学 家兔模型 治疗 蛇伤 |
| 文章编号： | 1001-5639(2003)03-0017-03 |
Pharmacy Study of Snakebite Tincture Against Cobratoxin |
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| JIANG San yuan,LI Jing xin,TANG Rong de,ZHANG Jian min,YU Nan fa,CHANG Shui ping.Pharmacy Study of Snakebite Tincture Against Cobratoxin[J].Journal of Snake,2003,15(3):17-19. |
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| Authors: | JIANG San yuan LI Jing xin TANG Rong de ZHANG Jian min YU Nan fa CHANG Shui ping |
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| Abstract: | Objective To explore the treatment effect of snakebite tincture against cobratoxin of Najanaja atra Methods The pathologic models and they were treated with snakebite tincture at locality of injected venom The toxic symptoms and blood indices were observed Results It was compared with the cobratoxin group that tincture group has some decrease in the symptoms of body and the rate of lethality, the varieties of WAS, CK, CRP were not such obvious and the levels PLT, PT, Fbg were not basically alterable Conclusion Snakebite tincture may relieve the inflammatory reaction, guard against the acute DIC and protect the tissues of body from the damage Thus, this tincture has better effect against cobratoxin |
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| Keywords: | Snakebite tincture Cobratoxin Rabbit model Pharmacy |
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