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C-cell follicles of canine thyroid glands studied by PAS reaction and electron microscopy
Authors:Dr. Yoko Kameda
Affiliation:(1) Department of Anatomy, Kawasaki Medical School, Kurashiki, Okayama, Japan;(2) Department of Anatomy, Kawasaki Medical School, 701-01 Kurashiki City, Okayama, Japan
Abstract:Summary Small follicles composed solely of C cells were occasionally observed in large C cell groups of dog thyroid glands. The lumina of C-cell follicles were filled with, or contained peripheral depositions of PAS-positive amorphous material, which was similar in ultrastructural features to thyroglobulin-containing colloid in typical thyroid follicles. This indicates that C cells, in addition to secreting calcitonin, produce a glycoprotein that can be stored in the lumina of the follicles.
Keywords:C cell  C-cell follicles  Colloid  PAS reaction  Glycoprotein
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