Proof-of-principle investigation of an algorithmic model of adenosine-mediated angiogenesis |
| |
| Authors: | Francisco Azuaje Frédérique Léonard Magali Rolland-Turner Yvan Devaux Daniel R Wagner |
| |
| Institution: | 1.Laboratory of Cardiovascular Research,Centre de Recherche Public - Santé (CRP-Santé),Luxembourg,Luxembourg;2.Division of Cardiology,Centre Hospitalier,Luxembourg,Luxembourg |
| |
| Abstract: | Background We investigated an algorithmic approach to modelling angiogenesis controlled by vascular endothelial growth factor (VEGF),
the anti-angiogenic soluble VEGF receptor 1 (sVEGFR-1) and adenosine (Ado). We explored its feasibility to test angiogenesis-relevant
hypotheses. We illustrated its potential to investigate the role of Ado as an angiogenesis modulator by enhancing VEGF activity
and antagonizing sVEGFR-1. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
