Calcitonin gene-related peptide-like immunoreactive cells in the secretory portions of rat sweat glands |
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Authors: | Akemi Ishida-Yamamoto Masaya Tohyama |
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Institution: | (1) Department of Anatomy II, Osaka University Medical School, Kitaku, Osaka, Japan;(2) Department of Antomy II, Osaka University Medical School, 4-3-57 Nakanoshima, Kitaku, 530 Osaka, Japan |
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Abstract: | Summary We found cells with calcitonin gene-related peptide-like immunoreactivity and with many cored vesicles in the secretory portions of sweat glands of rat foot pads. About 10% of sweat glands contained single immunoreactive cells. The immunoreactive cells were flaskshaped, with a narrow apex facing the glandular lumen and the bulk of the cell body in the basal half of the glandular wall. In the cytoplasm, there were many vesicles, 100–250 nm in diameter, with cores of various electron densities. These cytochemical and cytological characteristics suggest that the immunoreactive cells are homologous to gastrointestinal basal granulated cells. |
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Keywords: | Sweat glands Diffuse neuroendocrine system Basal granulated cells Neuropeptides Calcitonin gene-related peptide (CGRP) Rat (Wistar) |
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