A novel representation of RNA secondary structure based on element-contact graphs |
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| Authors: | Wenjie Shu Xiaochen Bo Zhiqiang Zheng Shengqi Wang |
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| Institution: | (1) Beijing Institute of Radiation Medicine, Beijing, 100850, China;(2) College of Electro-Mechanic and Automation, National University of Defense Technology, Changsha, Hunan, 410073, China |
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| Abstract: | Background Depending on their specific structures, noncoding RNAs (ncRNAs) play important roles in many biological processes. Interest
in developing new topological indices based on RNA graphs has been revived in recent years, as such indices can be used to
compare, identify and classify RNAs. Although the topological indices presented before characterize the main topological features
of RNA secondary structures, information on RNA structural details is ignored to some degree. Therefore, it is necessity to
identify topological features with low degeneracy based on complete and fine-grained RNA graphical representations. |
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