Studies on cell fusion between Babesia rodhaini-infected mouse erythrocytes and baby hamster kidney cells. |
| |
| Authors: | A D Irvin D A Stagg G K Kanhai C G Brown P L Omwoyo |
| |
| Institution: | UNDP/FAO Tick-borne Diseases Project, East African Veterinary Research Organization, Muguga, P.O. Box 32, Kikuyu, Kenya |
| |
| Abstract: | Heterokaryons were formed by fusion of B. rodhaini-infected mouse erythrocytes and baby hamster kidney (BHK) cells, using Sendai virus. The erythrocyte membrane rapidly lysed inside the BHK cell cytoplasm releasing free parasites. There was no evidence that parasite multiplication occurred inside the BHK cells, nor that parasitized BHK cells were infective for mice.Transient erythrocyte homokaryons were observed in some preparations.The approach indicates a possible method for the in vitro cultivation of Babesia. |
| |
| Keywords: | BHK cells cell fusion heterokaryon homokaryon erythrocyte mouse Sendai virus |
| 本文献已被 ScienceDirect 等数据库收录！ |
