Some observations on the behaviour of hypothalamic enzymes during the time of blastocyst implantation in the rabbit |
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| Authors: | K. C. Hooper |
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| Affiliation: | Agricultural Research Council Institute of Animal Physiology, Babraham, Cambridge and Department of Physiology, University of Birmingham |
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| Abstract: | 1. Hypothalami from pregnant and non-pregnant rabbits were homogenized in sucrose and separated into fractions by differential and density-gradient centrifugation. 2. The fractions were examined for enzymes capable of inactivating oxytocin. 3. Enzyme activity was detected in the supernatant and one particulate fraction of both pregnant and non-pregnant animals. 4. The specific activity of the enzymes increased during early pregnancy, and coincided with the time of blastocyst spacing and implantation in the uterus. |
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