Fast atom bombardment mass spectrometry of insulin, insulin A-chain, insulin B-chain, and glucagon

Fast atom bombardment mass spectral data are presented for the polypeptides insulin, oxidized insulin A-chain, carboxymethylated insulin B-chain, and glucagon. The doubly-charged molecular ion of the intact insulin molecule produced with fast atom bombardment with xenon atoms is observed at a reduced accelerating voltage (4 kV).