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Helicobacter pylori infection increases cell kinetics in human gastric epithelial cells without adhering to proliferating cells |
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| Authors: | Hayama Masayoshi Kawakami Yoshiyuki Kaneko Yasunori Sano Kenji Ota Hiroyoshi |
| Institution: | Department of Biomedical Laboratory Sciences, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, Nagano, 390-8621, Japan. mahayama@hsp.md.shinshu-u.ac.jp |
| Abstract: | We investigated the effect of H. pylori infection on cell proliferation of gastric mucosa using immunostaining for H. pylori or Ki67. H. pylori cells attached to surface mucous cells covering luminal surface and the upper part of gastric foveolae, and up-regulated the proliferative activity of gastric epithelial cells without adhering to the proliferating epithelial cells. |
| Keywords: | Helicobacter pylori gastric surface epithelial cell gastric proliferating zone gastric mucin immunohistochemistry |
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