A novel role of Ca2+ and Zn2+: Protection of cells against membrane damage |
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Authors: | C. A. Pasternak |
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Affiliation: | (1) Department of Biochemistry, St George's Hospital Medical School, Cranmer Terrace, SW17 0RE London, UK |
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Abstract: | Certain cytotoxic agents damage cells by the induction of pores across their plasma membrane. Ca2+ and Zn2+ protect against such damage by promoting pore closure. Zn2+ may play a beneficial role in this regard in certain disease states. |
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Keywords: | calcium zinc membrane protection |
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