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High levels of histone H3 acetylation at the CMV promoter are predictive of stable expression in Chinese hamster ovary cells |
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| Authors: | Benjamin Moritz Laura Woltering Peter B. Becker Ulrich Göpfert |
| Affiliation: | 1. Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Germany;2. Biomedical Center and Center for Integrated Protein Science, Molecular Biology Division, Ludwig‐Maximilians‐University, Munich, Germany |
| Abstract: | |
| Keywords: | CHO cells stability histone modification promoter methylation cell line development |