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Identifying a robust design space for glycosylation during monoclonal antibody production
Authors:Melissa M. St. Amand  James Hayes  Devesh Radhakrishnan  Janice Fernandez  Bill Meyer  Anne S. Robinson  Babatunde A. Ogunnaike
Affiliation:1. Dept. of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE;2. Biopharm Process Development, GlaxoSmithKline, King of Prussia, PA;3. Dept. of Chemical and Biomolecular Engineering, Tulane University, New Orleans, LA
Abstract:
Keywords:glycosylation  design space  QbD  bioreactor  CHO  DoE  enzyme expression  sugar nucleotide
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