Examination of platelet aggregation and ultrastructure in patients with non-Hodgkin's lymphoma |
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| Authors: | E Ignatova T Lissitschkov A Dobreva T Meschkov D Avramova |
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| Affiliation: | Wissenschaftlichen Institut für H?matologie und Bluttransfusion, Medizinischen Akademie Sofia, Bulgarien. |
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| Abstract: | Aggregation and secretion reaction of thrombocytes were studied in 54 patients suffering from Non-Hodgkin's++Lymphoma. Results were compared with electron-microscopic findings on thrombocytes of the same patients. Slight changes were found in stage II. In stage IV distinct therapy-resistant changes were noted in combination with storage pool disease syndrome which is to be considered as a consequence of impaired generation of thrombocytes in bone marrow. |
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