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Synthesis and antimycobacterial activity of ferrocenyl ethambutol analogues and ferrocenyl diamines
Authors:Razafimahefa Dorothée  Ralambomanana Dimby Andrianina  Hammouche Lies  Pélinski Lydie  Lauvagie Sylvia  Bebear Christiane  Brocard Jacques  Maugein Jeanne
Affiliation:Laboratoire de Chimie Appliquée aux Substances Naturelles, Faculté des Sciences d'Antananarivo, B.P. 906, 101 Antananarivo, Madagascar.
Abstract:A new series of ferrocenyl diamino alcohols and diamines were synthesized and their inhibitory potencies were probed with Mycobacterium tuberculosis. Interestingly, ferrocenyl diamines 6a and b display significant activities against M. tuberculosis H37Rv.
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