Spontaneous cleft palate in CF#1/Ohu mice] |
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| Authors: | Y Matsushima M Ohne T Irino M Maki |
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| Institution: | Department of Laboratory Animal Science, Ohu University, School of Dentistry, Fukushima, Japan. |
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| Abstract: | We found a spontaneous cleft palate in a mouse of CF#1/Ohu (Ohu University, Japan). Further, the frequency of the spontaneous cleft palate in strains of CF#1/Jms (Institute of Medical Science, University of Tokyo, Japan) and CF#1/Jah (National Institute of Animal Health, Japan) were about 3%, respectively. The frequency and the types of spontaneous cleft palate in CF#1 were clearly different from those in A/J and CL/Fr strains which were used as model animals of lip and cleft palate. We think that CF#1 is the new animal models to analyze a cleft palate genetically and biochemically. |
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