| 寡糖分离和结构分析进展 |
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| 引用本文： | 张剑波,田庚元.寡糖分离和结构分析进展[J].生物化学与生物物理进展,1998,25(2):114-119. |
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| 作者姓名： | 张剑波 田庚元 |
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| 作者单位： | 中国科学院上海有机化学研究所，上海 200032;中国科学院上海有机化学研究所，上海 200032 |
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| 摘 要： | 寡糖，尤其是糖缀合物中的寡糖链，在生命过程的细胞识别、信号传导和受体调节现象中扮演着重要的角色.高效液相色谱、毛细管电泳、质谱、核磁共振、荧光标记糖电泳和试剂阵列分析方法等新技术的应用使得寡糖的分离和结构鉴定变得更为快速、简便和准确；同时多种有力工具的联合运用将更深刻地揭示极微量寡糖的结构-功能关系成为可能.
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| 关 键 词： | 寡糖，分离，结构分析 |
| 收稿时间： | 1996/12/13 0:00:00 |
| 修稿时间： | 1997/6/23 0:00:00 |
Progress in Isolation and Structural Analysis of Oligosaccharides |
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| ZHANG Jian-bo and TIAN Geng-yuan.Progress in Isolation and Structural Analysis of Oligosaccharides[J].Progress In Biochemistry and Biophysics,1998,25(2):114-119. |
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| Authors: | ZHANG Jian-bo and TIAN Geng-yuan |
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| Institution: | Shanghai Institute of Organic Chemistry, The Chinese Academy of Sciences, Shanghai 200032, China;Shanghai Institute of Organic Chemistry, The Chinese Academy of Sciences, Shanghai 200032, China |
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| Abstract: | Oligosaccharides, especially the glycans on the glycoconjugates, play important roles in the cell recognition, signal transduction and receptor modulation phenomena in the life processes. The application of new techniques such as HPLC, capillary electrophoresis, MS, NMR, fluorophore-assisted carbohydrate electrophoresis and reagent array analysis method, allows the isolation and structural determination of oligosaccharide more rapid, convenient and accurate. Also it is now possible to understand more complete the structure-function relationship of the trace oligosaccharide, while a variety of powerful tools are combined. |
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| Keywords: | oligosaccharide isolation structural analysis |
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