A common sequence in the inverted terminal repetitions of human and avian adenoviruses |
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| Authors: | Peter Aleström Arne Stenlund Peng Li Ulf Pettersson |
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| Affiliation: | 1. Department of Microbiology, The Biomedical Center, Box 581, S-751 23 Uppsala Sweden;1. The John Curtin School of Medical Research, The Australian National University, Microbiology Department P.O. Box 334, Canberra City, A.C.T. 2601 Australia |
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| Abstract: | The termini of the avian chick embryo lethal orphan (CELO) virus DNA have been sequenced. The results revealed a 63-bp-long inverted terminal repetition (ITR) which shared the sequence ATAATA with all adenovirus termini, thus far analyzed. The CELO virus ITR differed from those of the mammalian adenoviruses in two major aspects: (i) it is not a perfect duplication; (ii) it begins with a 5'-guanylic acid residue instead of the cytidylic acid normally observed in adenoviruses. |
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| Keywords: | CELO virus DNA replication DNA sequence terminal protein bp base pairs CELO virus chick embryo lethal orphan virus ITR inverted terminal repetition |
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