Hematopoietic stem cells: multiparameter regulation |
| |
| Authors: | Kedong Song Liying Li Yiwei Wang Tianqing Liu |
| |
| Institution: | 1.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering,Dalian University of Technology,Dalian,China;2.Burns Research Group, ANZAC Research Institute,University of Sydney,Concord,Australia |
| |
| Abstract: | Hematopoietic stem cells (HSCs) are capable to self-renew with multi-potency which generated much excitement in clinical therapy. However, the main obstacle of HSCs in clinical application was insufficient number of HSCs which were derived from either bone marrow, peripheral blood or umbilical cord blood. This review briefly discusses the indispensable utility of growth factors and cytokines, stromal cells, extracellular matrix, bionic scaffold and microenvironment aiming to control the hematopoiesis in all directions and provide a better and comprehensive understanding for in vitro expansion of hematopoietic stem cells. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
