Picornaviruses of two different genera have similar structures |
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| Authors: | Ming Luo Edward Arnold John W Erickson Michael G Rossmann Ulrike Boege Douglas G Scraba |
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| Institution: | Department of Biological Sciences, Purdue University West Lafayette, Ind. 47907, U.S.A.;Department of Biochemistry, University of Alberta Edmonton, Alberta T6G 2H7, Canada |
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| Abstract: | Crystals of Mengo virus were used to collect three-dimensional X-ray diffraction data to 7 Å resolution. A self-rotation function showed the precise orientation of the Mengo particles in the crystal unit cell. A cross-rotation function against similar data of cubic rhinovirus crystals showed a peak when the orientations of these two icosahedral viruses were superimposed. This demonstrates similarity of capsid construction between two picornaviruses of different taxonomic genera. |
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