Excitatory and Inhibitory Neural Control of Airway Smooth Muscles and a Braking System for Airway Constriction |
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| Authors: | Email author" target="_blank">Y?ItoEmail author K?Shoudai N?Akaike |
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| Institution: | (1) Department of Pharmacology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;(2) Research Division for Life Sciences, Kumamoto Health Science University, Kumamoto, Japan |
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| Abstract: | The importance of parasympathetic excitatory and inhibitory neural control of airway smooth muscles has been demonstrated. It is concluded that excitatory (acetylcholine, ACh) and inhibitory (NO- and VIP-related) neurotransmitters co-exist and are co-released from vagus nerve terminals. The latter transmitters can directly relax airway smooth muscles and, at the same time, inhibit ACh release, playing the role of the braking system against bronchoconstriction.Neirofiziologiya/Neurophysiology, Vol. 37, No. 1, pp. 80–81, January–February, 2005. |
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| Keywords: | autonomic nervous system airway smooth muscles contraction relaxation NANC transmitters NO-related neurotransmitters prostaglandins braking system for airway constriction |
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