The influence of excessive dietary molybdenum on rat liver enzymes

• 1.1. The effects of feeding excessive sodium molybdate on liver enzymes of the rat was investigated.
• 2.2. A level of from 400 to 1200 p.p.m. molybdenum resulted in decreased growth and a reduction in food consumption.
• 3.3. The copper level of the diet was adequate to maintain normal blood hemoglobin and normal liver catalase and cytochrome oxidase.
• 4.4. The most striking alteration in pattern of liver enzymes was a marked increase in alkaline phosphatase activity which could not be correlated with the presence of an enzyme stimulator.