Proteomic studies in biomedically and industrially relevant fungi |
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Authors: | Stephen Carberry Sean Doyle |
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Institution: | (1) Department of Biology, National Institute for Cellular Biotechnology, National University of Ireland Maynooth, Maynooth, Co. Kildare, Ireland |
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Abstract: | Historically, the proteomic investigation of filamentous fungi has been restrained by difficulties associated with efficient
protein extraction and the lack of extensive fungal genome sequence databases. The advent of robust protein extraction and
separation technologies, combined with protein mass spectrometry and emerging genome sequence data, is leading to the emergence
of extensive new knowledge on the nature of these organisms. In this review, we discuss some recent technological advances
and their role in exploring the proteome of Aspergillus spp., along with other biotechnologically relevant fungi. |
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Keywords: | Aspergillus fumigatus Hypothetical protein identification Invasive aspergillosis MALDI-ToF Mass spectrometry Proteomics Fungal proteomics |
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