Functional diversity in the dynamin family |
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Authors: | van der Bliek A M |
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Affiliation: | Dept of Biological Chemistry, UCLA School of Medicine 90095-1737, USA. avan@mednet.ucla.edu |
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Abstract: | The function of the GTPase dynamin has been discussed for several years. It clearly plays a role in vesicle budding, but, despite recent insights, precisely how it functions in this process is still a matter of debate. In addition, it is now clear that dynamin is a member of a large protein family, present in a variety of cellular locations where members apparently perform a range of functions. This article describes current understanding of the structure and function of the various dynamin family members. |
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