Synthesis and biological activity of chloroethyl pyrimidine nucleosides |
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| Authors: | Colombeau Ludovic Teste Karine Hadj-Bouazza Amel Chaleix Vincent Zerrouki Rachida Kraemer Michel Catherine Odile Sainte |
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| Institution: | Université de Limoges, Laboratoire de Chimie des Substances Naturelles, Faculté des Sciences et Techniques, Limoges, France. |
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| Abstract: | The synthesis and biological activity of chloroethyl pyrimidine nucleosides is presented. One of these new nucleosides analogues significantly inhibited cell proliferation, migration and invasion as tested in vitro on the A431 vulvar epidermal carcinoma cell line. |
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