Hypogonadotroper Hypogonadismus aufgrund eines IHH oder Kallmann-Syndroms beim Mann |
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| Authors: | Prof Dr HM Behre F T??ttelmann S Ledig P Wieacker |
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| Institution: | 1. Zentrum f??r Reproduktionsmedizin und Andrologie, Universit?tsklinikum Halle (Saale), Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland
2. Institut f??r Humangenetik, Universit?tsklinikum M??nster, M??nster, Deutschland
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| Abstract: | The prevalence of isolated hypogonadotropic hypogonadism (IHH)/Kallmann syndrome in males is about 1:10,000. IHH is characterized by absent sexual development and low levels of gonadotropins and testosterone. Kallmann syndrome is characterized by the association of HH and total or partial loss of olfaction (in 60%). IHH/Kallmann syndrome are very heterogeneous disorders. Clinical and genetic diagnosis as well as therapy will be discussed. |
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