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Design,synthesis and biological evaluation of novel triazoloquinazolinone and imidazoquinazolinone derivatives as allosteric inhibitors of SHP2 phosphatase |
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| Authors: | Wenjun Ye Ye Liu Qian Ren Tianhui Liao Yumei Chen Dongmei Chen Sisi Wang Lihong Yao Yihe Jia Chunshen Zhao Zhixu Zhou |
| Affiliation: | aSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, China;bGuizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China;cDepartment of Medicinal Chemistry, China Pharmaceutical University, Nanjing, China |
| Abstract: | |
| Keywords: | SHP2 allosteric inhibitors synthesis antitumor activity |