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A new defect in the peripheral conversion of cortisone to cortisol |
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| Authors: | G Phillipou B A Higgins |
| Abstract: | A steroid disorder is described in two sisters, aged 13 and 17 years, in which the metabolism of cortisol results almost exclusively in urinary excretion of tetrahydro-cortisone (11-keto) derivatives. The evidence implies the existence of a deficiency in the peripheral enzymatic conversion of cortisone to cortisol. |
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