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Dynamic mechanical response of bovine gray matter and white matter brain tissues under compression
Authors:Farhana Pervin  Weinong W. Chen
Affiliation:1. Division of Neuronic Engineering, School of Technology and Health, Royal Institute of Technology, SE-141 52 Huddinge, Sweden;2. Materials Technology Institute, Eindhoven University of Technology, P.O. Box 513 MB Eindhoven, The Netherlands;1. Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA 01605, USA;2. Department of Mechanical Engineering, Worcester Polytechnic Institute, Worcester, MA 01609, USA;1. Department of Neurosurgery, NorthShore University Health System, 1001 University Place, Evanston, IL 60201, United States;2. Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, MC 8904, 1210 Amsterdam Avenue, New York, NY 10027, United States;3. MEA Forensic Engineers & Scientists, 22 Voyager Court South, Toronto, ON M9W 5M7, Canada;4. Department of Neurological Surgery, Columbia University Medical Center, New York Presbyterian Hospital, 710 West 168th Street, New York, NY 10032, United States;1. Mechatronic Systems Engineering, Simon Fraser University, Surrey, BC, Canada;2. California National Primate Research Center, University of California Davis, CA, USA;3. Department of Neurological Surgery, Brain and Spinal Injury Center, University of California at San Francisco, San Francisco, CA, USA;4. International Collaboration on Repair Discoveries (ICORD), Vancouver, BC, Canada
Abstract:Dynamic responses of brain tissues are needed for predicting traumatic brain injury (TBI). We modified a dynamic experimental technique for characterizing high strain-rate mechanical behavior of brain tissues. Using the setup, the gray and white matters from bovine brains were characterized under compression to large strains at five different strain rates ranging from 0.01 to 3000/s. The white matter was examined both along and perpendicular to the coronal section for anisotropy characterization. The results show that both brain tissue matters are highly strain-rate sensitive. Differences between the white matter and gray matter in their mechanical responses are recorded. The white matter shows insignificant anisotropy over all strain rates. These results will lead to rate-dependent material modeling for dynamic event simulations.
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