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Isolation and characterization of a fluorescent material in bovine achilles tendon collagen
Authors:Daisaburo Fujimoto  Kin-ya Akiba  Nobuo Nakamura
Affiliation:Hamamatsu University School of Medicine, Hamamatsu 431-31, Japan;Department of Chemistry, Faculty of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Abstract:A fluorescent material in bovine achilles tendon collagen was isolated and characterized by ultraviolet spectroscopy, fluorescence spectroscopy and nmr spectroscopy. The data suggest that the compound is a 3-hydroxypyridinium derivative with three amino acid side chains. The name “pyridinoline” is proposed. Pyridinoline is a novel type crosslink of collagen.
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