Isolation and characterization of a fluorescent material in bovine achilles tendon collagen |
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Authors: | Daisaburo Fujimoto Kin-ya Akiba Nobuo Nakamura |
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Affiliation: | Hamamatsu University School of Medicine, Hamamatsu 431-31, Japan;Department of Chemistry, Faculty of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan |
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Abstract: | A fluorescent material in bovine achilles tendon collagen was isolated and characterized by ultraviolet spectroscopy, fluorescence spectroscopy and nmr spectroscopy. The data suggest that the compound is a 3-hydroxypyridinium derivative with three amino acid side chains. The name “pyridinoline” is proposed. Pyridinoline is a novel type crosslink of collagen. |
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