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Potentiation of mitogen-induced lymphocyte stimulation by polyethylene glycols |
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| Authors: | W.G. Bessler L. Schimmelpfeng J.H. Peters |
| Affiliation: | 1. Institut für Mikrobiologie II der Universität Tübingen, Germany;2. Institut für Genetik der Universität Köln, Germany |
| Abstract: | The effect of polyethylene glycols of different molecular weights on mitogen-induced lymphocyte stimulation was investigated. The stimulation obtained by neuraminidase/galactose oxidase treatment, and by addition of several plant lectin mitogens, was markedly enhanced in the presence of polyethylene glycols of molecular weights ranging from 6 000 to 40 000. Optimal potentiation of stimulation was found for polyethylene glycol concentrations up to about 5 %. |
| Keywords: | ConA concanavalin A LcA lentil lectin LIMA lima bean lectin LP lipoprotein LPS lipopolysaccharide MW molecular weight PEG polyethylene glycol[s] PHA phytohemagglutinin PWM pokeweed mitogen SBL soy bean lectin |
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