A cell surface alteration in mouse L cells induced by interferon |
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| Authors: | Ernest Knight Bruce D. Korant |
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| Affiliation: | Central Research & Development Department Experimental Station E. I. du Pont de Nemours and Company Wilmington, Delaware 19898 USA |
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| Abstract: | Mouse L cells grown in suspension culture when treated with L cell interferon have a greater electrophoretic mobility toward the anode than control cells. This change in electrophoretic mobility depends on the concentration of interferon in the medium and the duration of interferon interaction with the cells. It is concluded that the interferon-treated cells have a greater net negative charge on the cell surface than control cells and it is suggested that the cell surface is altered because of the interaction with interferon. |
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