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Chemical Constituents of Phacellaria compressa Benth.
Authors:Xiu-Yun Zhang  Bo-Gang Li  Min Zhou  Xiao-Hong Yuan   Guo-Lin Zhang
Affiliation:Chengdu Institute of Biology, the Chinese Academy of Sciences, Chengdu 610041, China;;Graduate School of the Chinese Academy of Sciences, Beijing 100039, China;;College of Life Sciences, Northwest Agricultural University, Yangling 712100, China
Abstract:Two new compounds, 1-(3-methoxy-4-hydroxyphenyl)-3-(3, 5-dimethoxy-4-hydroxyphenyl)-propane (1) and 5, 7,3'-trimethyoxyflavan-4'-O-β-D-glucopyranoside (2) were isolated from the ethanol extract of the dried aerial parts of Phacellaria compressa Benth., together with 2,3-bis[(4-hydroxy-3,5-dimethoxyphenyl)-methyl]-1,4-butanediol (3), ethyl 3,4,5-trihydroxybenzoate (4), methyl 3, 4, 5-trihydroxybenzoate (5), β-sitosterol (6), 5, 7, 3', 4'-tetrahydroxyflavan (7), lupeol (8), zhebeiresinol (9), quercetin-3-O-α-L-rhamnopyranoside (10), (+)-catechin (11),betulin (12), β-daucosterol (13), (+)-syringaresinol (14), scopoletin (15), and proximadiol (16). The structures of these compounds were determined by spectral evidence or by comparing them with authentic samples.Compound 9 showed α-amylase inhibitory activity of 57.55% at a concentration of 50 μg/mL.
Keywords:1,3-diphenyl-propane  Phacellaria compressa
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