Age-related changes in lipid peroxidation in various structures of the central nervous system |
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| Authors: | I A Volchegorskii S E Shemyakov I B Telesheva N V Malinovskaya V V Turygin |
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| Institution: | (1) Chelyabinsk State Medical Academy, Chelyabinsk, Russia |
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| Abstract: | Age-related changes in contents of lipid peroxidation (LPO) products and sensitivity to oxidative stress were studied in ten structures of the human brain and three parts of the spinal cord. LPO was found to increase with age in all parts of the central nervous system. This regularity was especially pronounced in the brainstem structures (the hypothalamus, mesencephalon, and myelencephalon) and in the cervical and sacrolumbar enlargements of the spinal cord.Translated from Fiziologiya Cheloveka, Vol. 31, No. 2, 2005, pp. 108–115.Original Russian Text Copyright © 2005 by Volchegorskii, Shemyakov, Telesheva, Malinovskaya, Turygin. |
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