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Pharmacological activities of crude acetone extract and purified constituents of Salvia moorcraftiana Wall. |
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| Authors: | T. Khan M. Zahid M. Asim Shahzad ul-Hussan Z. Iqbal M. Iqbal Choudhary V. Uddin Ahmad |
| Affiliation: | aResearch Institute of Pharmaceutical Sciences, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan bInternational Center for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi, Pakistan cDepartment of Pharmacy University of Peshawar, Peshawar, Pakistan, Pakistan |
| Abstract: | The crude acetone extract of aerial parts of Salvia moorcraftiana Wall. was screened for various biological activities including Lemna bioassay, antifungal, antibacterial, leishmanicidal, insecticidal activities and brine shrimp cytotoxicity. It was found to possess strong phytotoxic activity against Lemna aequinoctials Welve. and moderate antifungal activity against animal and plant pathogens. The purified chemical constituents were tested for enzyme inhibition activity. Two constituents (compounds 3 and 8) were found to be effective inhibitors of alpha-glucosidase. |
| Keywords: | Salvia moorcraftiana phytotoxicity antifungal activity enzyme inhibition activity |
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