Bifurcation structure of a model of bursting pancreatic cells |
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Authors: | Mosekilde E Lading B Yanchuk S Maistrenko Y |
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Institution: | Department of Physics, Center for Chaos and Turbulence Studies, Building 309, The Technical University of Denmark, 2800 Kgs., Lyngby, Denmark. ellen@chaos.fys.dtu.dk |
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Abstract: | One- and two-dimensional bifurcation studies of a prototypic model of bursting oscillations in pancreatic beta-cells reveal a squid-formed area of chaotic dynamics in the parameter plane, with period-doubling bifurcations on one side of the arms and saddle-node bifurcations on the other. The transition from this structure to the so-called period-adding structure is found to involve a subcritical period-doubling bifurcation and the emergence of type-III intermittency. The period-adding transition itself is not smooth but consists of a saddle-node bifurcation in which (n+1)-spike bursting behavior is born, slightly overlapping with a subcritical period-doubling bifurcation in which n-spike bursting behavior loses its stability. |
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